AMRscape

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ESKAPE Resistome Comparison Explorer

Pick two ESKAPE pathogens from the dropdowns at the top to compare their antibiotic resistance profiles.

Explore the charts — radar profiles, drug class coverage, WHO AWARE tier exposure, mobilization breakdown, and more.

Check the comparison zone for the Venn overlap, Therapeutic Escape Index (★ novel metric), and clinical risk indicators.

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Compare antibiotic resistance profiles across ESKAPE pathogens · Select two organisms to explore mechanisms, drug class coverage, and co-infection risk

—ARG Similarity

—Shared ARGs

— Ther. Escape Index ★

—HGT-risk Shared ARGs ⓘ

—Reserve Drugs at Risk

Resistance Mechanism Profile ⓘ

WHO AWARE Exposure ⓘ

Mobilization ⓘ

Drug Class Resistance Map ⓘ

Resistance Mechanism Profile ⓘ

WHO AWARE Exposure ⓘ

Mobilization ⓘ

Drug Class Resistance Map ⓘ

Comparative Analysis

ARG Overlap (Venn) ⓘ

Therapeutic Escape Index ★ ⓘ

Mechanism Burden Comparison ⓘ

Risk Indicators

Data Sources

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CARD 2025

Comprehensive Antibiotic Resistance Database — ARO accessions, gene names, resistance mechanisms, curated ESKAPE resistomes

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UniProt REST API

Protein sequences, Pfam domain cross-references and protein names for each AMR gene (live API)

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STRING (live API)

Protein–protein interaction scores ≥0.70 used as co-resistance network edges per ESKAPE taxon

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WHO AWARE 2025

Access / Watch / Reserve antibiotic classification — 2025 edition, updated every 2 years by WHO Expert Committee

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WHO Priority Pathogens 2024

Bacterial pathogens of public health importance — Critical / High priority classification for ESKAPE organisms

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Therapeutic Escape Index (TEI) — Novel metric

% of WHO-classified drug classes where a co-infection scenario has no shared susceptibility. Computed from CARD + WHO AWARE 2025. Developed for AMRscape.

📄 How to cite AMRscape

AMRscape

Comparative Analysis

Resistance Gene Profiles

Data Sources